Cat. No. 1387
Biological ActivityPotent, selective partial agonist peptide for the NOP receptor (Ki = 0.71 nM). Selective over μ, δ and κ opioid receptors (IC50 > 4000 nM). Increases food intake in vivo.
(Modifications: Arg-1 = C-terminal Ac, Lys-6 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ho et al (2000) Characterization of the ORL1 receptor on adrenergic nerve in the rat anococcygeus. Br.J.Pharmacol. 131 349. PMID: 10991930.
Dooley et al (1997) Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1. J.Pharmacol.Exp.Ther. 283 735. PMID: 9353393.
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Keywords: Ac-RYYRWK-NH2, supplier, Potent, selective, NOP, partial, agonists, peptide, Nociceptin, Receptors, ORL1, OP4, Opioid, Tocris Bioscience, NOP Receptor Agonist products
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March 1, 2017
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