Cat. No. 1387
Biological ActivityPotent, selective partial agonist peptide for the NOP receptor (Ki = 0.71 nM). Selective over μ, δ and κ opioid receptors (IC50 > 4000 nM). Increases food intake in vivo.
(Modifications: Arg-1 = C-terminal Ac, Lys-6 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Ho et al (2000) Characterization of the ORL1 receptor on adrenergic nerve in the rat anococcygeus. Br.J.Pharmacol. 131 349. PMID: 10991930.
Dooley et al (1997) Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1. J.Pharmacol.Exp.Ther. 283 735. PMID: 9353393.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Ac-RYYRWK-NH2 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Ac-RYYRWK-NH2, supplier, Potent, selective, NOP, partial, agonists, peptide, Nociceptin, Receptors, ORL1, OP4, Opioid, Tocris Bioscience, NOP Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Fluorescent opioid antagonist; fluorescent-derivative of naloxone (Cat. No. 0599)BMS 986187
Potent δ-opioid receptor positive allosteric modulator
April 10 - 13, 2017