Pancreatic Polypeptide (human)
Cat. No. 1154
Biological ActivityEndogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.
(Modifications: Tyr-36 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Gehlert (1998) Multiple receptors for the pancreatic polypeptide (PP-fold) family: physiological implications. Proc.Soc.Exp.Biol.Med. 218 7. PMID: 9572148.
Michel et al (1998) XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143. PMID: 9549761.
Bard et al (1995) Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. J.Biol.Chem. 270 26762. PMID: 7592911.
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Keywords: Pancreatic Polypeptide (human), supplier, NPY, Y4, agonist, involved, gastrointestinal, tract, function, Neuropeptide, Y, Receptors, neuropeptides, Tocris Bioscience, NPY Receptor Agonist products
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