Bombinakinin M

Cat. No. 2371

Bombinakinin M Asp-Leu-Pro-Lys-Ile-Asn-Arg-Lys-Gly-ProArg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

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Alternative Name: Maximakinin

Biological Activity

Potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth muscle of guinea pig ileum (EC50 = 4.0 nM).

Technical Data

M.Wt:
2179.55
Formula:
C100H159N31O24
Sequence:
DLPKINRKGPRPPGFSPFR
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
509151-65-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Lee et al (2005) Cloning of bradykinin precursor cDNAs from skin of Bombina maxima reveals novel bombinakinin M antagonists and a bradykinin potential peptide. Regul.Peptides 127 207.

O'Rourke et al (2004) The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima. Regul.Peptides 121 65.

Lai et al (2001) A novel bradykinin-related peptide from skin secretions of toad Bombina maxima and its precursor containing six identicals copies of the final product. Biochem.Biophys.Res.Comm. 286 259.

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Keywords: Bombinakinin M, supplier, Potent, bradykinin, receptor, agonists, B1, B2, Receptors, Bradykinin, BombinakininM, Tocris Bioscience, Bradykinin Receptor Agonist products

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