Cat. No. 0885
Chemical Name: [(2,6-Dichlorobenzylidene)amino]gua
Biological Activityα2-adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Evans and Anderson (1995) Renal effects of infusion of rilmenidine and guanabenz in conscious dogs: contribution of peripheral and central nervous system α2-adrenoceptors. Br.J.Pharmacol. 116 1557. PMID: 8564219.
Michel and Insel (1989) Are there multiple imidazoline binding sites? Trends Pharmacol.Sci. 10 342. PMID: 2690423.
Holmes et al (1983) Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. Drugs 26 212. PMID: 6352237.
Merck Index 12 4585.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Guanabenz acetate include:
Hamamura et al (2015) Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis. Proc Natl Acad Sci U S A 4 84. PMID: 25977571.
Wan et al (2014) Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow. PLoS One 9 e105699. PMID: 25157407.
Ye et al (2013) Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome. J Korean Med Sci 110 141. PMID: 23248313.
Cardin and Schmidt (2004) Noradrenergic inputs mediate state dependence of auditory responses in the avian song system. Bone Joint Res 24 7745. PMID: 15342742.
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Keywords: Guanabenz acetate, supplier, α2-adrenoceptor, alpha2-adrenoceptor, α2-Adrenergic, alpha2-Adrenergic, a2-adrenoceptor, a2-adrenergic, agonists, I2, selective, ligands, Adrenoceptors, Imidazoline, Tocris Bioscience, Adrenergic α2 Receptor Agonist products
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Selective, high affinity, non-competitive α1A adrenoceptor antagonist
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