Cat. No. 2334
Biological ActivityEndocytosis inhibitor that blocks the interaction of dynamin with amphiphysin 1 and 2. Impairs AMPA receptor cycling and blocks DHPG-induced long term depression (LTD).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Xiao et al (2001) Metabolic glutamate receptor activation causes a rapid redistribution of AMPA receptors. Neuropharmacology 41 664. PMID: 11640920.
Lüscher et al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649. PMID: 10595516.
Wigge and McMahon (1998) The amphiphysin family of proteins and their role in endocytosis at the synapse. Trends Neursci. 21 339.
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Citations are publications that use Tocris products.
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Keywords: D15, supplier, Endocytosis, blockers, impairs, AMPA, receptor, cycling, dynamin, amphiphysin, 1, 2, Tocris Bioscience, Translocation, Exocytosis & Endocytosis products
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