Ro 10-5824 dihydrochloride
Cat. No. 2329
Chemical Name: 5-[(3,6-Dihydro-4-phenyl-1(2H)-pyri
Biological ActivitySelective dopamine D4 receptor partial agonist (EC50 = 205 nM) that binds with high affinity (Ki = 5.2 nM). Displays 250-fold selectivity over D3 receptors and > 1000-fold selectivity over D2, D1 and D5 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Powell et al (2003) RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology 44 473. PMID: 12646284.
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Keywords: Ro 10-5824 dihydrochloride, supplier, Selective, D4, receptor, partial, agonists, Dopamine, Receptors, dopaminergic, Ro10-5824, dihydrochloride, Tocris Bioscience, D4 Receptor Agonist products