Cat. No. 0926
Alternative Name: β-FNA
Chemical Name: (E)-4-[[5α,6β)-17-Cyclopropylmethyl)-
Biological ActivitySelective μ opioid receptor antagonist.
Licensing InformationSold with the permission of the University of Minnesota
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Jiang et al (1990) μ Antagonist and κ agonist properties of β-funaltrexamine (β-FNA) in vivo: long lasting spinal analgesia in mice. J.Pharmacol.Exp.Ther. 252 1006. PMID: 2156986.
Takemorei et al (1981) The irreversible narcotic antagonist and reversible agonist properties of the fumarate methyl ester derivative of naltrexone. Eur.J.Pharmacol. 70 445. PMID: 6263637.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for β-Funaltrexamine hydrochloride include:
Tzeng et al (2011) Myricetin Ameliorates Defective Post-Receptor Insulin Signaling via β-Endorphin Signaling in the Skeletal Muscles of Fructose-Fed Rats. Evid Based Complement Alternat Med 2011 150752. PMID: 21785619.
Largent-Milnes et al (2010) Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance. Br J Pharmacol 161 986. PMID: 20977451.
Cecchi et al (2008) Differential responses to morphine-induced analgesia in the tail-flick test. Behav Brain Res 194 146. PMID: 18656501.
Do you know of a great paper that uses β-Funaltrexamine hydrochloride from Tocris? If so please let us know.
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July 29 - 31, 2016