Pravastatin sodium salt
Cat. No. 2318
Alternative Name: Eptastatin sodium
Chemical Name: (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-
Biological ActivityWater-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Hamelin and Turgeon (1998) Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors. TiPS 19 26. PMID: 9509899.
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Citations are publications that use Tocris products. Selected citations for Pravastatin sodium salt include:
Vainio et al (2011) Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. Proc Natl Acad Sci U S A 2 1176. PMID: 22202492.
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Keywords: Pravastatin sodium salt, supplier, HMG-CoA, reductases, inhibitors, inhibits, Tocris Bioscience, HMG-CoA Reductase Inhibitor products
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