Cat. No. 2315
Chemical Name: 4-(1H-Imidazol-4-ylmethyl)pyridine dihydrobromide
Biological ActivityPotent and highly selective histamine H3 receptor agonist (pEC50 = 9.74) that displays 300-fold selectivity over the H4 receptor (pKi values are 9.07 and 6.61 respectively). Does not bind to H1 or H2 receptors at concentrations up to 10 μM. .
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kitbunnadaj et al (2004) Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H3 receptor agonist. J.Med.Chem. 47 2414. PMID: 15115383.
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Keywords: Immethridine dihydrobromide, supplier, Potent, H3, agonists, selective, over, H4, Receptors, Histamine, histaminergic, Tocris Bioscience, Histamine H3 Receptor Agonist products