Cat. No. 0701
Chemical Name: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-(
Biological ActivityA very potent and selective ligand for the D2 receptor (Ki = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D2 and a 12-fold lower affinity at 5-HT2 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Mach et al (1992) Effect of N-alkylation on the affinities of analogues of spiperone for dopamine D2 and serotonin 5-HT2 receptors. J.Med.Chem. 35 423. PMID: 1531364.
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Keywords: 3'-Fluorobenzylspiperone maleate, supplier, D2-like, ligand, Dopamine, Non-Selective, Receptors, dopaminergic, 3-Fluorobenzylspiperone, maleate, Tocris Bioscience, Non-selective Dopamine Ligand products
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