Cat. No. 0522
Chemical Name: (E)-1-[Bis(4-fluorophenyl)methyl]-4
Biological ActivityDual Na+/Ca2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Urenjak and Obrenovitch (1996) Pharmacological modulation of voltage gated Na+ channels: a rational and effective strategy against ischemic brain damage. Pharmacol.Rev. 48 21. PMID: 8685246.
Eichler et al (1994) The ability of diphenylpiperazines to prevent neuronal death in dorsal root ganglion neurons in vitro after axotomy. J.Neurochem. 62 2148. PMID: 8189223.
Pauwels et al (1991) Ca+ and Na+ channels involved in neuronal cell death - protection by flunarizine. Life.Sci. 48 1881. PMID: 1850815.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Flunarizine dihydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Flunarizine dihydrochloride, supplier, Dual, Na+/Ca2+, channel, T-type, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Na+, Calcium, CaV, Ca2+, Tocris Bioscience, Voltage-gated Sodium (NaV) Channel Blocker products
Find multiple products by catalog number
New Products in this Area
Potent and selective Nav1.7 channel blockerOD1
Potent hNav1.4, rNav1.6 and rNav1.7 channel activatorMambalgin 1
Selective ASIC1a inhibitor; analgesic
October 30 - November 3, 2016
Boston, MA, USA