Cat. No. 2307
Alternative Names: LTB4, 5,12-DiHETE
Chemical Name: (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydro
Biological ActivityPotent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Yokomitso et al (2001) Leukotriene B4: metabolism and signal transduction. Arch.Biochem.Biophys. 385 231. PMID: 11368003.
Ford-Hutchinson (1990) Leukotriene B4 in inflammation. Crit.Rev.Immunol. 10 1. PMID: 2155000.
Bray et al (1981) Leukotriene B4: an inflammatory mediator in vivo. Prostaglandins 22 213. PMID: 6270742.
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Keywords: Leukotriene B4, supplier, BLT1, BLT2, receptor, agonists, potent, Receptors, leukotrienes, eicosanoids, LeukotrieneB4, Tocris Bioscience, Leukotriene and Related Receptor Agonist products
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