15-deoxy-Δ-12,14-Prostaglandin J2

Cat. No. 2306

15-deoxy-D-12,14-Prostaglandin J2 C20H28O3 [87893-55-8]

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Chemical Name: (5Z,12E,14E)-11-Oxo-prosta-5,9,12,14-tetraen-1-oic acid

Biological Activity

Selective PPARγ agonist that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC50 = 7 μM).

Technical Data

M.Wt:
316.44
Formula:
C20H28O3
Solubility:
Soluble in Methyl acetate (supplied pre-dissolved - 1mg/ml)
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
87893-55-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Forman et al (1995) 15-Deoxy-Δ12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83 803. PMID: 8521497.

Kliewer et al (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813. PMID: 8521498.

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Keywords: 15-deoxy-D-12,14-Prostaglandin J2, supplier, Endogenous, PPARγ, PPARgamma, agonists, Peroxisome, Proliferator-activating, Receptors, 15-deoxy-Delta-12, 14-Prostaglandin, J2, 15-deoxy-D-1214-ProstaglandinJ2, Tocris Bioscience, PPARγ Agonist products

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