(±)-Cloprostenol sodium salt
Cat. No. 2295
Chemical Name: (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R
Biological ActivityWater-soluble prostaglandin F2α (PGF2α) analog; acts as a potent FP receptor agonist (EC50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Serrero and Lepak (2002) Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm. 233 200.
Griffin et al (1998) Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 286 411. PMID: 9655886.
Dukes et al (1974) Potent luteolytic agents related to prostaglandin F2α. Nature 250 330. PMID: 4853720.
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Keywords: (±)-Cloprostenol sodium salt, supplier, Water-soluble, PGF2alpha, potent, FP, receptor, agonists, Receptors, Prostaglandin, Prostanoid, Tocris Bioscience, Prostanoid Receptor Agonist products
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