(±)-Cloprostenol sodium salt

Cat. No. 2295

()-Cloprostenol sodium salt C22H28ClNaO6 [55028-72-3]

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Chemical Name: (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid monosodium salt

Biological Activity

Water-soluble prostaglandin F2α (PGF2α) analog; acts as a potent FP receptor agonist (EC50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.

Technical Data

M.Wt:
446.9
Formula:
C22H28ClNaO6
Solubility:
Soluble to 20 mM in water
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
55028-72-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Serrero and Lepak (2002) Prostaglandin F receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm. 233 200.

Griffin et al (1998) Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 286 411. PMID: 9655886.

Dukes et al (1974) Potent luteolytic agents related to prostaglandin F. Nature 250 330. PMID: 4853720.

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Keywords: ()-Cloprostenol sodium salt, supplier, Water-soluble, PGF2alpha, potent, FP, receptor, agonists, Receptors, Prostaglandin, Prostanoid, Tocris Bioscience, Prostanoid Receptor Agonist products

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