EGLU

Cat. No. 0971

EGLU C7H13NO4 [170984-72-2]

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Chemical Name: (2S)-α-Ethylglutamic acid

Biological Activity

Selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord; presumed group II mGlu receptor antagonist. Also available as part of the Group II mGlu Receptor Tocriset™.

Technical Data

M.Wt:
175.18
Formula:
C7H13NO4
Solubility:
Soluble to 100 mM in 1eq. NaOH
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
170984-72-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Jane et al (1996) Potent antagonists at L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate recpetors in neonatal rat spinal cord. Neuropharmacology 35 1029. PMID: 9121605.

Thomas et al (1996) (S)-α-Ethylglutamic acid and (RS)-α-cyclopropyl-4-phosphonophenylglycine as antagonists of L-AP4- and (1S,3S)-ACPD-induced depression of monosynaptic excitation of neonatal rat motoneurones. Br.J.Pharmacol. 117 70P.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for EGLU include:

Smith and Otis (2005) Pattern-dependent, simultaneous plasticity differentially transforms the input-output relationship of a feedforward circuit. Proc Natl Acad Sci U S A 102 14901. PMID: 16199519.

Do you know of a great paper that uses EGLU from Tocris? If so please let us know.

View Related Products by Target

Keywords: EGLU, supplier, selective, group, II, mGlur, antagonist, Group, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, Tocris Bioscience, Glutamate (Metabotropic) Group II Receptor Antagonist products

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