Cat. No. 2288
Chemical Name: 1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3
Biological ActivitySelective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).
Licensing InformationSold under license from the NIH, US patent 60/312,674
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hoi and Hiley (2006) Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. Br.J.Pharmacol. 147 560. PMID: 16415907.
Mo et al (2004) Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go coupled receptor distinct from CB1, CB2 or EDG-1. Eur.J.Pharmacol. 489 21. PMID: 15063151.
Offertáler et al (2003) Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Mol.Pharmacol. 63 699. PMID: 12606780.
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Keywords: O-1918, supplier, Silent, antagonists, putative, abnormal-CBD, receptor, cannabinoids, Receptors, 0-1918, Tocris Bioscience, Other Cannabinoid products