Cat. No. 0438
Chemical Name: 1-Ethyl-4-[(1-methylethylidene)hydr
Biological ActivityPhosphodiesterase inhibitor, selective for PDE4 (IC50 = 2.0 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Ahluwalia and Nicholson et al (1991) Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. TiPS 12 19. PMID: 1848733.
Rhoads (1982) Selective inhibition of cyclic AMP and cyclic GMP phosphodiesterases of cardiac nuclear fraction. Biochem.Pharmacol. 31 665. PMID: 6177320.
Chesin et al (1972) 1-Ethyl-4-(isopropylidenehydrazinol-H-pyrazolo-(3,4-b)-pyridin-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009) - potent new inhibitor of cyclic 3'5-nucleotide phosphodiesterase. Biochem.Pharmacol. 21 2443. PMID: 4345859.
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Keywords: Etazolate hydrochloride, supplier, PDE4, inhibitors, inhibits, PDE, Phosphodiesterases, Tocris Bioscience, Phosphodiesterase Inhibitor products
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