EIT hydrobromide

Cat. No. 0873

EIT hydrobromide C3H8N2S.HBr [1071-37-0]

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Chemical Name: (S)-Ethylisothiourea hydrobromide

Biological Activity

Potent, selective and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).

Technical Data

M.Wt:
185.08
Formula:
C3H8N2S.HBr
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
1071-37-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Data Sheet: View Safety Data Sheet

Squadrito et al (1996) Effects of S-ethylisothiourea, a potent inhibitor of nitirc oxide synthase, alone or in combination with a nitric oxide donor in splanchnic artery occlusion shock. Br.J.Pharmacol. 119 23. PMID: 8872352.

Nakane et al (1995) Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol.Pharmacol. 47 831. PMID: 7536889.

Garvey et al (1994) Potent and selective inhibition of human nitric oxide synthase. J.Biol.Chem. 269 26669. PMID: 7523409.

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Keywords: EIT hydrobromide, supplier, Selective, iNOS, inhibitors, inhibits, arginine, binding, site, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, Tocris Bioscience, iNOS Inhibitor products

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