Dobutamine hydrochloride

Cat. No. 0515

Dobutamine hydrochloride C18H23NO3.HCl [49745-95-1]

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Chemical Name: 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride

Biological Activity

β1- and β2-adrenoceptor agonist with some action at the α1-adrenoceptor.

Technical Data

Soluble to 100 mM in DMSO
>99 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Deighton et al (1992) Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, dopamine, dobutamine, denopamine and xamoterol in isolated human right atrium. J.Pharmacol.Exp.Ther. 262 532. PMID: 1354251.

Brown et al (1987) Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium. Naunyn Schmiedebergs Arch.Pharmacol. 335 385. PMID: 3600817.

Merck Index 12 3456.

If you know of a relevant reference for Dobutamine hydrochloride please let us know.

Citations are publications that use Tocris products. Selected citations for Dobutamine hydrochloride include:

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Biol Reprod 329 350. PMID: 19144685.

Skeberdis et al (1997) Pharmacological characterization of the receptors involved in the beta-adrenoceptor-mediated stimulation of the L-type Ca2+ current in frog ventricular myocytes. Br J Pharmacol 121 1277. PMID: 9257904.

Do you know of a great paper that uses Dobutamine hydrochloride from Tocris? If so please let us know.

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