Cat. No. 2277

MNI-caged-D-aspartate C13H15N3O6 [845555-94-4]

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Alternative Name: 4-Methoxy-7-nitroindolinyl-caged-D-aspartate

Chemical Name: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid

Biological Activity

D-aspartate caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Photolyzed by UV light with a quantum efficiency of 0.09 at pH 7.4. Agonist at NMDA receptors and EAAT substrate.

Licensing Information

Sold under license from the UK Medical Research Council

Technical Data

Soluble to 5 mM in water and to 10 mM in DMSO
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Huang et al (2005) Synthesis and characterization of 4-methoxy-7-nitroindolinyl-D-aspartate, a caged compound for selective activation of glutamate transporters and N-methyl-D-aspartate receptors in brain tissue. Biochemistry 44 3316. PMID: 15736942.

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Keywords: MNI-caged-D-aspartate, supplier, MNI-caged-D-aspartate, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Caged, Compounds, EAAT, excitatory, amino, acid, transporters, Tocris Bioscience, Photolysis products

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