Cat. No. 2276
Chemical Name: 7-[3-(4-Acetyl-3-hydroxy-2-propylph
Biological ActivityLeukotriene receptor antagonist; inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Folkerts et al (1995) Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur.J.Pharmacol. 285 R1. PMID: 8566126.
O'Donnell and Welto (1984) Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions 14 43. PMID: 6322547.
Jones et al (1983) Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachealis: interaction with FPL-55712. Prostaglandins 26 833. PMID: 6322240.
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Keywords: FPL 55712, supplier, leukotrienes, eicosanoids, receptor, antagonists, CysLT1, Receptors, receptors, LTD4, LTE4, FPL55712, Tocris Bioscience, Leukotriene and Related Receptor Antagonist products
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