OR-486

Cat. No. 0483

OR-486 C6H4N2O6 [7659-29-2]

Price and Availability

For OR-486 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 3,5-Dinitrocatechol

Biological Activity

Potent and selective inhibitor of catechol-O-methyl-transferase.

Technical Data

M.Wt:
200.11
Formula:
C6H4N2O6
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
7659-29-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
Select another batch:

Mannisto and Kaakola (1990) Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease. Pharmacol.Toxicol. 66 317. PMID: 2196554.

Borgulya et al (1989) Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies. Helv.Chim.Acta 72 952.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for OR-486 include:

Oróstica et al (2014) Estradiol increases cAMP in the oviductal secretory cells through a nongenomic mechanism. Reproduction 148 285. PMID: 25038866.

Do you know of a great paper that uses OR-486 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: OR-486, supplier, Catechol, O-methyl, transferase, COMT, inhibitors, inhibits, Tocris Bioscience, Catechol O-Methyltransferase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

New Products in this Area

BMS 795311

Potent cholesteryl ester transfer protein (CETP) inhibitor

Perhexiline maleate

Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor

MS 023 dihydrochloride

Potent and selective type I PRMT inhibitor

Sign-up for new product e-alerts
divider line

Bio-Techne Events

One Day Symposium

Bio-Techne Symposium 2017

Epigenetic Regulation of Stem Cell Differentiation

March 1, 2017

Amsterdam, The Netherlands