Cat. No. 2261
Chemical Name: 3-[[(2R)-2-Hydroxypropyl]amino]-3-m
Biological ActivityHighly potent, non-peptide ghrelin receptor (GHS-R1a) agonist (Ki = 0.8 nM). Increases plasma GH levels in vivo and is 2- to 2.5-fold more potent than GHRP-6.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Glavaski-Joksimovic et al (2002) Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropes. J.Endocrinol. 175 625. PMID: 12475374.
Smith et al (1999) Peptidomimetic regulation of growth hormone secretion. Endocrine Rev. 18 621.
Jacks et al (1994) Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. J.Endocrinol. 143 399. PMID: 7830002.
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Keywords: L-692,585, supplier, Potent, non-peptide, ghrelin, receptors, agonists, GHS-R1a, Receptors, Growth, Hormone, Secretagog, 1a, Ghrelin, L692585, Tocris Bioscience, Ghrelin Receptor Agonist products
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