GLP-2 (human)

Cat. No. 2258

GLP-2 (human) His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp

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Alternative Name: Glucagon-like peptide 2 (human)

Biological Activity

Endogenous peptide identified as an intestinal epithelium-specific growth factor; stimulates cell proliferation and inhibits apoptosis. Diverse effects on gastrointestinal function including regulation of intestinal glucose transport, food intake, and gastric acid secretion.

Technical Data

M.Wt:
3766.14
Formula:
C165H254N44O55S
Sequence:
HADGSFSDEMNTILDNLAARDFINWLIQTKITD
Solubility:
Soluble to 1 mg/ml in 5% NH4OH / water
Storage:
Desiccate at -20°C
CAS No:
223460-79-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Brubaker and Drucker (2004) Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinol. 145 2653.

Bulut et al (2004) Glucagon-like peptide 2 improves intestinal wound healing through induction of epithelial cell migration in vitro-evidence for a TGF-β-mediated effect. Reg.Peptides 121 137.

Rocha et al (2004) Glucagon-like peptide-2: divergent signalling pathways. J.Surg.Res. 121 5. PMID: 15313368.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for GLP-2 (human) include:

Baldassano et al (2009) Glucagon-like peptide-2 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro. Am J Physiol Gastrointest Liver Physiol 297 G800. PMID: 19628655.

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Keywords: GLP-2 (human), supplier, Endogenous, hormone, displays, intestinotrophic, activity, GLP2, Receptors, Glucagon-Like, Peptide, 2, Glucagon, like, peptide2, (human), Tocris Bioscience, Glucagon-Like Peptide 2 Receptor products

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