2,4-Dihydroxyphenylacetyl-L-asparagine

Cat. No. 0262

2,4-Dihydroxyphenylacetyl-L-asparagine C12H14N2O6 [111872-98-1]

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Biological Activity

Constituent of various spider toxins. Reported to be specific blocker of glutamate receptors.

Technical Data

M.Wt:
282.25
Formula:
C12H14N2O6
Solubility:
Soluble to 50 mM in water
Storage:
Desiccate at -20°C
CAS No:
111872-98-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Usherwood et al (1990) Mechanisms of neurotoxicity of low molecular weight spider toxins. Basic Science in Toxicology. Ed. G.N. Volans 569.

Pan-Hou et al (1989) A spider toxin (JSTX) inhibits L-glutamate uptake by rat brain synaptosomes. Brain Res. 476 354. PMID: 2564797.

Pan-Hou et al (1987) Inhibitory effect of 2,4-dihydroxyphenylacetylasparagine, a common moiety of spider toxin, on glutamate binding to rat brain synaptic membranes. Neurosci.Lett. 81 199. PMID: 2827066.

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Keywords: 2,4-Dihydroxyphenylacetyl-L-asparagine, supplier, Component, Joro, spider, toxin, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, antagonists, blockers, Tocris Bioscience, Miscellaneous Glutamate products

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