Cat. No. 0262
Biological ActivityConstituent of various spider toxins. Reported to be specific blocker of glutamate receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Usherwood et al (1990) Mechanisms of neurotoxicity of low molecular weight spider toxins. Basic Science in Toxicology. Ed. G.N. Volans 569.
Pan-Hou et al (1989) A spider toxin (JSTX) inhibits L-glutamate uptake by rat brain synaptosomes. Brain Res. 476 354. PMID: 2564797.
Pan-Hou et al (1987) Inhibitory effect of 2,4-dihydroxyphenylacetylasparagine, a common moiety of spider toxin, on glutamate binding to rat brain synaptic membranes. Neurosci.Lett. 81 199. PMID: 2827066.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 2,4-Dihydroxyphenylacetyl-L-asparagine from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: 2,4-Dihydroxyphenylacetyl-L-asparagine, supplier, Component, Joro, spider, toxin, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, antagonists, blockers, Tocris Bioscience, Miscellaneous Glutamate products
Find multiple products by catalog number
New Products in this Area
Potent NMDA receptor antagonist; NR2A selectivecis-6-Hydroxynorketamine hydrochloride
Metabolite of ketamine (Cat.No. 3131); antidepressive
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.