Quercetin

Cat. No. 1125

Quercetin C15H10O7 [117-39-5]

Price and Availability

For Quercetin pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Biological Activity

Antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca2+ and K+ channels and behaves as an agonist at estrogen (GPER) receptors.

Technical Data

M.Wt:
302.24
Formula:
C15H10O7
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
117-39-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Cermak et al (2002) The flavonol quercetin activates basolateral K+ channels in rat distal colon epithelium. Br.J.Pharmacol. 135 1183. PMID: 11877325.

Saponara et al (2002) Quercetin as a novel activator of L-type Ca2+ channels in rat tail artery smooth muscle cells. Br.J.Pharmacol. 135 1819. PMID: 11934824.

Wei et al (1994) Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res. 54 4952. PMID: 8069862.

Levy et al (1984) Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin. Biochem.Biophys.Res.Commun. 123 1227. PMID: 6091650.

Graziani et al (1983) The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo. J.Biochem. 135 583. PMID: 6311542.

Merck Index 12 8216.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Quercetin include:

Filone et al (2014) The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. PLoS Pathog 10 e1003904. PMID: 24516381.

Do you know of a great paper that uses Quercetin from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Quercetin, supplier, Non-Selective, PI, 3-kinase, inhibitors, GPR30, agonists, non-selective, 3-Kinase, PI3K, Akt, Signaling, Signalling, PIP2, Inositol, Lipids, cAMP, Receptors, Estrogen, receptors, Phosphoinositide, Kinases, GPER, Tocris Bioscience, PI 3-kinase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Kinase Inhibitor Toolbox

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Kinases Product Listing

Kinases Product Listing

Highlights over 400 products for kinase research. Request copy or view PDF today.

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

Pain Research Product Guide

Pain Research Product Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Life Science Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance. Request copy today.

divider line

New Products in this Area

MP A08

Selective ATP competitive SphK1 and 2 inhibitor; cell permeable

Akti-1/2

Potent and selective dual Akt1 and 2 inhibitor

VX 680

High affinity and selective Aurora kinase inhibitor

Imatinib mesylate

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

TGX 221

Potent and selective PI 3-kinase β inhibitor

PF 543 hydrochloride

Potent and selective SphK1 inhibitor

JX 06

Potent and selective PDK1/2/3 inhibitor

MRT 68601 hydrochloride

Potent TBK1 inhibitor

Azoramide

Unfolded protein response (UPR) modulator

LCB 03-0110 dihydrochloride

Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk

CCT 241533 dihydrochloride

Potent Chk2 inhibitor

IRAK1/4 Inhibitor I

IRAK4 and IRAK1 inhibitor

Centrinone

High affinity and selective PLK4 inhibitor

AZD 3147

Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable

Tilfrinib

Potent and selective breast tumor kinase (Brk) inhibitor

Prostratin

PKC activator; also NF-κB activator

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Physiology 2016

Physiology 2016

July 29 - 31, 2016

Dublin, Ireland

Booth: 26