Cat. No. 0475
Chemical Name: 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-
Biological ActivityPartial α-adrenergic agonist. Partial D2 dopaminergic receptor agonist. Competitive 5-HT antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Lesage et al (1998) Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. Br.J.Pharmacol. 123 1655. PMID: 9605573.
Doggrell et al (1992) Further analysis of the inhibitory effects of dihydroergotamine, cyproheptadine and ketanserin on the responses of the rat aorta to 5-hydroxytryptamine. J.Auton.Pharmacol. 12 223. PMID: 1512277.
Villalon et al (1992) Effects of S9977 and dihydroergotamine in an animal experimental model for migraine. Pharmacol.Res. 25 125. PMID: 1635891.
de Boer et al (1991) Carotid vascular effects of ergotamine and dihydroergotamine in the pig: no exclusive mediation via 5-HT1-like receptors. Br.J.Pharmacol. 104 183. PMID: 1664762.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Dihydroergotamine mesylate from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Dihydroergotamine mesylate, supplier, 5-HT, antagonists, partial, agonists, a-adrenergic, α-adrenergic, alpha-adrenergic, dopaminergic, D2, receptors, Partial, D2-like, alpha, Non-Selective, Serotonin, 5-HT3, Receptors, 5-Hydroxytryptamine, Dopamine, α-adrenoceptors, α-adrenoceptor, alpha-adrenoceptors, a-adrenoceptors, Tocris Bioscience, Non-selective Adrenergic α Receptor Agonist products