TCS 183

Cat. No. 2236

TCS 183 Met-Ser-Gly-Arg-Pro-Arg-Thr-Thr-Ser-Phe-Ala-Glu-Ser-NH2

Price and Availability

For TCS 183 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Fragment 1-13 of human and mouse GSK-3β sequence. Potentially useful as a competitive inhibitor of GSK-3β (Ser9) phosphorylation. Control peptide TCS 184 available (Cat. No. 2320).

Technical Data

M.Wt:
1425.58
Formula:
C58H96N20O20S
Sequence:
MSGRPRTTSFAES

(Modifications: Ser-13 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Peineau et al (2007) GSK3β mediates a novel interaction between LTP and LTD in the hippocampus. Neuron 53 703. PMID: 17329210.

If you know of a relevant reference for TCS 183 please let us know.

Citations are publications that use Tocris products. Selected citations for TCS 183 include:

Peineau et al (2007) LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron 53 703. PMID: 17329210.

Do you know of a great paper that uses TCS 183 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: TCS 183, supplier, Fragment, 1-13, GSK-3β, GSK-3beta, sequence, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, TCS183, Tocris Bioscience, Glycogen Synthase Kinase 3 products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Kinase Inhibitor Toolbox

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Kinases Product Listing

Kinases Product Listing

Our Kinase listing highlights over 400 products for kinase research. Request copy or view PDF today.

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

Schizophrenia Life Science Poster

Written by J. Lieberman

Schizophrenia Life Science Poster

Our Schizophrenia poster higlights the targets and pathways representing the most promising strategies to pursue for novel drug development. Request copy today.

divider line

Alzheimer's Life Science Poster

Written by Alan Palmer

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease. Request copy or view PDF today.

divider line

New Products in this Area

HS 38

ATP-competitive inhibitor of DAPK and ZIPK

st-Ht31 P

Negative control for st-Ht31 (Cat. No. 6286)

st-Ht31

Inhibits PKA/AKAP interactions; cell permeable

P21d hydrochloride

Potent and selective Brk inhibitor

CVT 313

cdk2 inhibitor

TPPB

High affinity PKC activator; also APP modulator

JH 295

Irreversible Nek2 inhibitor

OXSI 2

Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes

STK16-IN-1

Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases.

AZ PFKFB3 26

Potent and selective PFKFB3 inhibitor

NCL 00017509

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

XMD 8-87

Potent Ack1/TNK2 inhibitor

SKI 178

Non-lipid sphingosine kinase 1 (SphK1) inhibitor

ML 315 hydrochloride

Inhibitor of Clk and DYRK kinases

Everolimus

mTOR inhibitor;immunosuppressant

PKI (5-24)

High affinity PKA inhibitor

TDZD 8

Selective non-ATP competitive inhibitor of GSK 3β

BI 605906

Selective IKKβ inhibitor

GSK 319347A

Potent and selective IKKε inhibitor

FRAX 597

Potent group I PAK inhibitor

MRT 68921 dihydrochloride

Potent ULK inhibitor; inhibits autophagy

AM 2394

Potent glucokinase activator; orally bioavailable

eCF 309

Potent mTOR inhibitor

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.