Cat. No. 2235
Biological ActivityNovel phosphopeptide derived from GSK-3 recognition motif that acts as a substrate-competitive inhibitor of GSK-3β (IC50 = 150 μM). Displays minimal inhibition of Cdc2, MAPK, PKA, CK2, PKCδ and PKB at 200 μM. Myristoylated version available (L803-mts, Cat. No. 2256).
Licensing InformationSold under licence from Tel Aviv University Future Technology LP
(Modifications: Ser-10 = pSer)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Plotkin et al (2003) Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J.Pharmacol.Exp.Ther. 305 974. PMID: 12626660.
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Keywords: L803, supplier, Substrate-competitive, inhibitors, inhibits, GSK-3, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, Tocris Bioscience, Glycogen Synthase Kinase 3 Inhibitor products
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