FURA-2AM

Cat. No. 2220

FURA-2AM C44H47N3O24 [108964-32-5]

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Chemical Name: 2-[6-[bis[2-[(Acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid (acetyloxy)methyl ester

Biological Activity

Fluorescent Ca2+ indicator. Selective for Ca2+ over other divalent cations Mg2+, Zn2+, Fe2+ and Mn2+. Used to determine intracellular Ca2+ concentration.

Technical Data

M.Wt:
1001.85
Formula:
C44H47N3O24
Solubility:
Soluble to 10 mM in DMSO
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
108964-32-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Wang et al (2008) Sildenafil inhibits human pulmonary artery smooth muscle cell proliferation by decreasing capacitative Ca2+ entry. J.Pharmacol.Sci. 108 71. PMID: 18818482.

Grynkiewicz et al (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J.Biol.Chem. 260 3440. PMID: 3838314.

If you know of a relevant reference for FURA-2AM please let us know.

Citations are publications that use Tocris products. Selected citations for FURA-2AM include:

Luo et al (2015) Ketamine attenuates the Na+-dependent Ca2+ overload in rabbit ventricular myocytes in vitro by inhibiting late Na+ and L-type Ca2+ currents. Mol Neurodegener 36 1327. PMID: 26456586.

Bayliss and Evans (2013) Characterisation of AmphiAmR11, an amphioxus (Branchiostoma floridae) D2-dopamine-like G protein-coupled receptor. PLoS One 8 e80833. PMID: 24265838.

Do you know of a great paper that uses FURA-2AM from Tocris? If so please let us know.

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Keywords: FURA-2AM, supplier, Fluorescent, Ca2+, indicator, Probes, Calcium, Signaling, Signalling, Agents, General, Tocris Bioscience, Fluorescent Probe products

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