Cat. No. 0389
Chemical Name: N,N'-1,4-Butanediylbisguanidine sulfate
Biological ActivityNO synthase inhibitor. An NMDA antagonist acting as a competitive inhibitor at the polyamine site.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Doyle and Shaw (1998) Investigation of the actions and antagonist activity of some polyamine analogues in vivo. Br.J.Pharmacol. 124 386. PMID: 9641557.
Yokoi et al (1994) Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain. Neuropharmacology 33 1261. PMID: 7532812.
Reynolds (1990) Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. Eur.J.Pharmacol. 177 215. PMID: 2155812.
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Keywords: Arcaine sulfate, supplier, Competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor Antagonist products