TCS JNK 5a

Cat. No. 2827

TCS JNK 5a C20H16N2OS [312917-14-9]

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Chemical Name: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

Biological Activity

Selective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively). Displays no significant activity at a range of other protein kinases including EGFR, ErbB2, cdk2, PLK-1 and Src (pIC50 < 5.0).

Technical Data

M.Wt:
332.42
Formula:
C20H16N2OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
312917-14-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Angell et al (2007) N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg.Med.Chem.Letts. 17 1296.

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Keywords: TCS JNK 5a, supplier, Selective, inhibitors, JNK2, JNK3, Mitogen-Activated, Protein, Kinases, MAPK, c-Jun, N-Terminal, SAPKs, Stress-Activated, TCSJNK5a, Tocris Bioscience, JNK/c-Jun Inhibitor products

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