D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
Cat. No. 1482
Biological ActivityImportant second messenger involved in Ca2+ mobilization from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467. PMID: 9850611.
Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223. PMID: 8913354.
Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077. PMID: 6607924.
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