Cat. No. 1485
Alternative Name: Docosatetraenylethanolamide
Chemical Name: N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-d
Biological ActivityPotent endocannabinoid and anandamide (Cat. No. 1339) analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Cannabimimetic in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Walter et al (2001) Microglial cells produce endocannabinoids and express functional cannabinoid receptors: evidence that docosatetraenylethanolamide (DEA) is an additional endocannabinoid. Soc.Neurosci.Abstr. 634.16.
Barg et al (1995) Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. Eur.J.Pharmacol. 287 145. PMID: 8749028.
Hanus et al (1993) Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J.Med.Chem. 36 3032. PMID: 8411021.
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Keywords: DEA, supplier, Endogenous, CB1, agonists, Cannabinoids, Receptors, cb1r, Tocris Bioscience, CB1 Receptor Agonist products