NocII

Cat. No. 1119

NocII Phe-Ser-Glu-Phe-Met-Arg-Gln-Tyr-Leu-Val-Leu-Ser-Met-Gln-Ser-Ser-Gln

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Biological Activity

Orphan neuropeptide, flanking nociceptin in the precursor pronociceptin. Stimulates locomotion in mice, possibly through a novel specific receptor.

Technical Data

M.Wt:
2081.4
Formula:
C92H141N23O28S2
Sequence:
FSEFMRQYLVLSMQSSQ
Solubility:
Soluble in water
Storage:
Desiccate at -20°C
CAS No:
188119-47-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Florin et al (1999) Comparison of behavioural effects of NocII or NocIII, two related pronociceptin-derived peptides. Life Sci. 65 2727. PMID: 10622282.

Florin et al (1997) Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. NeuroReport 8 705. PMID: 9106751.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for NocII include:

Laudenbach et al (2001) Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain. J Clin Invest 107 457. PMID: 11181645.

Do you know of a great paper that uses NocII from Tocris? If so please let us know.

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Keywords: NocII, supplier, Orphan, neuropeptide, Nociceptin, Receptors, ORL1, OP4, NOP, Opioid, neuropeptides, Tocris Bioscience, NOP Receptor products

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