Cat. No. 0125
Chemical Name: DL-2-Amino-3-phosphonopropionic acid
Biological ActivityCompetitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hawkinson et al (1996) The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase. Eur.J.Pharmacol. 307 219. PMID: 8832224.
Saugstad et al (1995) L-2-Amino-3-phosphonopropionic acid completely antagonizes metabotropic glutamate receptors 1α and 5 in Xenopus oocytes. Eur.J.Pharmacol. 289 395. PMID: 7621916.
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. PMID: 7042024.
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Keywords: DL-AP3, supplier, Phosphoserine, phosphatase, inhibitors, inhibits, Group, I, mGlur, antagonists, Protein, Ser/Thr, Phosphatases, Receptors, mGlu1, mGlu5, mGluR1, mGluR5, Glutamate, Metabotropic, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products
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