IRL-1038

Cat. No. 1195

IRL-1038 Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: 1 - 5)

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Biological Activity

ETB endothelin receptor antagonist.

Technical Data

M.Wt:
1410
Formula:
C68H92N14O15S2
Sequence:
CVYFCHLDIIW

(Modifications: Disulfide bridge between 1 - 5)

Solubility:
Soluble to 1 mg/ml in 20% acetonitrile
Storage:
Desiccate at -20°C
CAS No:
144602-02-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Haynes et al (1993) Endothelin; progress in pharmacology and physiology. TiPS 14 225. PMID: 8372400.

Karaki et al (1993) ETB receptor antagonist, IRL 1038, selectively inhibits the endothelin-induced endothelium-dependent vascular relaxation. Eur.J.Pharmacol. 231 371. PMID: 8449230.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for IRL-1038 include:

Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607. PMID: 16432510.

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Keywords: IRL-1038, supplier, ETB, antagonists, Receptors, Endothelin, Tocris Bioscience, ETB Receptor Antagonist products

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