Cat. No. 1195
Biological ActivityETB endothelin receptor antagonist.
(Modifications: Disulfide bridge between 1 - 5)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Haynes et al (1993) Endothelin; progress in pharmacology and physiology. TiPS 14 225. PMID: 8372400.
Karaki et al (1993) ETB receptor antagonist, IRL 1038, selectively inhibits the endothelin-induced endothelium-dependent vascular relaxation. Eur.J.Pharmacol. 231 371. PMID: 8449230.
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Citations are publications that use Tocris products. Selected citations for IRL-1038 include:
Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607. PMID: 16432510.
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Keywords: IRL-1038, supplier, ETB, antagonists, Receptors, Endothelin, Tocris Bioscience, ETB Receptor Antagonist products