(±)-Anatoxin A fumarate
Cat. No. 0789
Chemical Name: (±)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate
Biological ActivityA potent nicotinic agonist (Ki values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors respectively). Stimulates [3H]-dopamine release from rat striatal synaptosomes (EC50 = 136 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Sharples et al (2000) UB-165 implicates α4β2 nAChR in striatal dopamine release. J.Neurosci. 20 2783. PMID: 10751429.
Thomas et al (1993) (+)-Anatoxin is a potent agonist at neuronal nicotinic acetylcholine receptors. J.Neurochem. 60 2308. PMID: 8492133.
Gordon et al (1992) Induced release of acetylcholine from guinea pig ileum longitudinal muscle myenteric plexus by anatoxin-A. J.Pharmacol.Exp.Ther. 263 997. PMID: 1469655.
Stolerman et al (1992) Behavioural effects of anatoxin, a potent nicotinic agonist in rats. Neuropharmacology 31 311. PMID: 1630597.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for (±)-Anatoxin A fumarate include:
Gagnon and Pick (2012) Effect of nitrogen on cellular production and release of the neurotoxin anatoxin-a in a nitrogen-fixing cyanobacterium. Front Microbiol 3 211. PMID: 22701451.
Do you know of a great paper that uses (±)-Anatoxin A fumarate from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: (±)-Anatoxin A fumarate, supplier, Nicotinic, agonists, Acetylcholine, Receptors, Non-Selective, nAChR, (±)-AnatoxinA, fumarate, Tocris Bioscience, Nicotinic Receptor (Non-selective) Agonist products
Find multiple products by catalog number
March 18 - 22, 2017
Little Rock, ARK, USA