Ghrelin (human)

Cat. No. 1463

Ghrelin (human) Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

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Biological Activity

Endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.

Licensing Information

This peptide is distributed under license from Dr. Kangawa

Technical Data

M.Wt:
3370.9
Formula:
C149H249N47O42
Sequence:
GSSFLSPEHQRVQQRKESKKPPAKLQPR

(Modifications: Ser-3 = Ser(n-octanoyl))

Solubility:
Soluble to 2 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
258279-04-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Inui (2001) Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat.Rev.Neurosci. 2 551. PMID: 11483998.

Tolle et al (2001) In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology 73 54. PMID: 11174017.

Kojima et al (1999) Ghrelin is growth-hormone-releasing acylated peptide from stomach. Nature 402 656. PMID: 10604470.

If you know of a relevant reference for Ghrelin (human) please let us know.

Citations are publications that use Tocris products. Selected citations for Ghrelin (human) include:

Rodríguez et al (2009) Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes. Sci Signal 33 541. PMID: 19238155.

Do you know of a great paper that uses Ghrelin (human) from Tocris? If so please let us know.

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Keywords: Ghrelin (human), supplier, Endogenous, ghrelin, receptor, agonists, GHS-R1a, Receptors, Growth, Hormone, Secretagog, Receptor, 1a, peptides, acylated, Tocris Bioscience, Ghrelin Receptor Agonist products

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