Cat. No. 2168
Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Gln-Met-
Biological ActivityCaspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.
(Modifications: Asp-1 = Z-Asp(OMe), Asp-4 = (OMe)-fluoromethylketone)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bang et al (2004) Differential response to MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents. Biochem.Pharmacol. 68 659. PMID: 15276073.
Chou et al (2004) Alterations in protein kinase C activity and processing during zinc deficiency-induced cell death. Biochem.J. 383 63. PMID: 15198639.
Izban et al (2001) Characterization of NF-κB expression in Hodgkin's disease: inhibition of constitutively expressed NF-κB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells. Mod.Pathol. 14 297. PMID: 11301346.
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Keywords: Z-DQMD-FMK, supplier, Caspase-3, inhibitors, inhibits, Caspases, Proteinases, Proteases, Tocris Bioscience, Caspase Inhibitor products
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