Cat. No. 2168
Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Gln-Met-
Biological ActivityCaspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.
(Modifications: Asp-1 = Z-Asp(OMe), Asp-4 = (OMe)-fluoromethylketone)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bang et al (2004) Differential response to MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents. Biochem.Pharmacol. 68 659. PMID: 15276073.
Chou et al (2004) Alterations in protein kinase C activity and processing during zinc deficiency-induced cell death. Biochem.J. 383 63. PMID: 15198639.
Izban et al (2001) Characterization of NF-κB expression in Hodgkin's disease: inhibition of constitutively expressed NF-κB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells. Mod.Pathol. 14 297. PMID: 11301346.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Z-DQMD-FMK from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Z-DQMD-FMK, supplier, Caspase-3, inhibitors, inhibits, Caspases, Proteinases, Proteases, Tocris Bioscience, Caspase Inhibitor products
Find multiple products by catalog number
New Products in this Area
High affinity angiotensin-converting enzyme (ACE) ligandTMI 1
Adam 17 (TACE) and MMP inhibitor; orally bioavailableRitonavir
HIV-1 and HIV-2 protease inhibitorAcetyl Pepstatin
High affinity aspartic protease inhibitor; inhibits HIV-1/2 proteinasesONO 6818
High affinity and selective human neutraphil elastase 1 (HNE1) inhibitor; orally active
November 12 - 16, 2016
San Diego, CA, USA