Linomide

Cat. No. 1461

Linomide C18H16N2O3 [84088-42-6]

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Chemical Name: 1,2-Dihydro-4-hydroxy-N,N-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide

Biological Activity

Immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T cells and inhibits angiogenesis in rats in vivo.

Technical Data

M.Wt:
308.33
Formula:
C18H16N2O3
Solubility:
Soluble to 100 mM in 1.1eq. NaOH
Purity:
>99 %
Storage:
Store at RT
CAS No:
84088-42-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Gonzalo et al (1994) Linomide inhibits programmed cell death of peripheral T cells in vivo. Eur.J.Immunol. 24 48. PMID: 8020570.

Vukanovic et al (1993) Antiangiogenic effects of the quinoline-3-carboxamide linomide. Cancer Res. 53 1833. PMID: 7682157.

Ichikawa et al (1992) The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers. Cancer Res. 52 3022. PMID: 1591718.

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Keywords: Linomide, supplier, Immunomodulators, antiangiogenics, Tocris Bioscience, Antiangiogenic products

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