Etomidate

Cat. No. 1471

Etomidate C14H16N2O2 [33125-97-2]

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Chemical Name: (R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester

Biological Activity

General anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with β2- and β3-subunit containing GABAA receptors. Short acting and potent hypnotic, with low toxicity.

Technical Data

M.Wt:
244.29
Formula:
C14H16N2O2
Solubility:
Soluble to 100 mM in ethanol and to 50 mM in 1eq. HCl
Purity:
>99 %
Storage:
Store at RT
CAS No:
33125-97-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Moody et al (1998) Distinct structural requirements for the direct and indirect actions of the anaesthetic etomidate at GABAA receptors. Toxicol.Lett. 100-101 209. PMID: 10049144.

Belelli et al (1997) The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid. Proc.Natl.Acad.Sci.U.S.A. 94 11031. PMID: 9380754.

Giese et al (1983) Etomidate: a new intravenous anesthetic induction agent. Pharmacother. 3 251. PMID: 6359080.

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Keywords: Etomidate, supplier, GABA, mimetic, modulatory, agent, GABAA, Receptors, Tocris Bioscience, GABAA Receptor Modulator products

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