Cat. No. 1158
Biological ActivityEndogenous potent vasoconstrictor peptide. Stimulates the synthesis and release of aldosterone.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Potts et al (1999) Activation of brain neurons by circulating angiotensin II: direct effects and baroreceptor-mediated secondary effects. Neuroscience 90 581. PMID: 10215161.
Clayton et al (1998) Effects of prostaglandins and nitric oxide on the renal effects of angiotensin II in the anaesthetised rat. Br.J.Pharmacol. 124 1467. PMID: 9723960.
Mosequeda-Garcia et al (1990) Cardiovascular effects of microinjection of angiotensin II in the brainstem of renal hypertensive rats. J.Pharmacol.Exp.Ther. 255 374. PMID: 2213569.
If you know of a relevant reference for Angiotensin II please let us know.
Citations are publications that use Tocris products. Selected citations for Angiotensin II include:
Klingerman et al (2016) Acute Metabolic Effects of Olanzapine Depend on Dose and Injection Site. Dose Response 13 1559325815618910. PMID: 26740814.
Rodrigues-Diez et al (2015) The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells. Hum Mol Genet 22 29. PMID: 25065408.
Felizola et al (2014) PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues. Proc Natl Acad Sci U S A 52 159. PMID: 24403568.
Nistala et al (2010) Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome. J Mol Endocrinol 19 4790. PMID: 20871099.
Vinciguerra et al (2009) Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity. Aging (Albany NY) 2 43. PMID: 20228935.
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Keywords: Angiotensin II, supplier, Potent, vasoconstrictor, peptide, AT, Receptors, Non-Selective, Angiotensin, AngiotensinII, Tocris Bioscience, Non-selective AT Receptor Agonist products