Cat. No. 0370
Chemical Name: N-(6-Aminohexyl)-5-chloro-2-naphtha
Biological ActivityCalmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 72 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 78 4354. PMID: 6945588.
Hidaka et al (1979) Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. Mol.Pharmacol. 15 49. PMID: 218093.
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Keywords: W-9 hydrochloride, supplier, Calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Ca2+-calmodulin-dependent, phosphodiesterase, Tocris Bioscience, Calcium Binding Protein Modulator Antagonist products