Cat. No. 0787
Biological ActivityIrreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Huang et al (2009) Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect. Int.J.Radiat.Oncol.Biol.Phys. 74 237. PMID: 19362242.
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204. PMID: 9226999.
Laszlo et al (1995) Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur.J.Pharmacol. 272 169. PMID: 7536162.
Griffiths et al (1993) Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br.J.Pharmacol. 110 963. PMID: 7507781.
If you know of a relevant reference for Aminoguanidine hydrochloride please let us know.
Citations are publications that use Tocris products. Selected citations for Aminoguanidine hydrochloride include:
Jakubowska et al (2016) Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biol. 6 160149. PMID: 27488376.
Do you know of a great paper that uses Aminoguanidine hydrochloride from Tocris? If so please let us know.
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Keywords: Aminoguanidine hydrochloride, supplier, Irreversible, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, Tocris Bioscience, iNOS Inhibitor products
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