A-7 hydrochloride

Cat. No. 0378

A-7 hydrochloride C20H29ClN2O2S.HCl [79127-24-5]

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Chemical Name: N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

Biological Activity

Potent calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 3 μM).

Technical Data

M.Wt:
433.44
Formula:
C20H29ClN2O2S.HCl
Solubility:
Soluble to 50 mM in DMSO
Storage:
Store at RT
CAS No:
79127-24-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Itoh and Hidaka (1984) Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. J.Biochem. 96 1721. PMID: 6099352.

Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 102 185. PMID: 6139736.

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Keywords: A-7 hydrochloride, supplier, Calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Ca2+-calmodulin-dependent, phosphodiesterase, Tocris Bioscience, Calcium Binding Protein Modulator Antagonist products

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