Cat. No. 0258
Chemical Name: 1-Aminocyclobutane-1-carboxylic acid
Biological ActivityNMDA receptor partial agonist, acting at the glycine site of NR1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Inanobe et al (2005) Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron 47 71. PMID: 15996549.
Rao et al (1990) Neuropharmacological characterization of 1-aminocyclopropane-1-carboxylate and 1-aminocyclobutane-1-carboxylate, ligands of the N-methyl-D-aspartate-associated glycine receptor. Neuropharmacology 29 305. PMID: 2158004.
Hood et al (1989) 1-Aminocyclobutane-1-carboxylic acid (ACBC): a specific antagonist of the NMDA receptor coupled glycine receptor. Eur.J.Pharmacol. 161 281. PMID: 2542048.
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Citations are publications that use Tocris products.
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Keywords: ACBC, supplier, NMDA, antagonists, glycine, site, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor Antagonist products