3-Aminobenzamide

Cat. No. 0788

3-Aminobenzamide C7H8N2O [3544-24-9]

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Alternative Name: 3-ABA

Biological Activity

An inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.

Technical Data

M.Wt:
136.15
Formula:
C7H8N2O
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
3544-24-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Cuzzocrea et al (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br.J.Pharmacol. 121 1065. PMID: 9249240.

Malorni et al (1995) 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem.Biophys.Res.Commun. 207 715. PMID: 7864864.

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Keywords: 3-Aminobenzamide, supplier, PARP, inhibitors, inhibits, PolyADP-ribose, Polymerases, Tocris Bioscience, Poly(ADP-Ribose) Polymerase Inhibitor products

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