Cat. No. 0666
Chemical Name: 3-(4-Allylpiperazin-1-yl)-2-quinoxa
Biological ActivityA competitive 5-HT3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Buznikov et al (2005) The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochem.Res. 30 825. PMID: 16187217.
Durk et al (2005) 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int.Immunol. 17 599. PMID: 15802305.
Monge et al (1993) Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J.Med.Chem. 36 2745. PMID: 8410988.
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Keywords: 3-AQC, supplier, 5-HT3, antagonists, Serotonin, Receptors, Tocris Bioscience, 5-HT3 Receptor Antagonist products