Ionomycin free acid

Cat. No. 2092

Ionomycin free acid C41H72O9 [56092-81-0]

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Chemical Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid

Biological Activity

Calcium ionophore; more specific than A23187 (Cat. No. 1234).

Technical Data

M.Wt:
709.01
Formula:
C41H72O9
Solubility:
Soluble to 10 mM in ethanol and to 10 mM in DMSO
Storage:
Desiccate at -20°C
CAS No:
56092-81-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Elzi et al (2001) Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 281 C350. PMID: 11401859.

Kaufmann et al (1980) Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 255 2735. PMID: 6766939.

Liu and Hermann (1978) Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 253 5892. PMID: 28319.

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Keywords: Ionomycin free acid, supplier, Calcium, ionophore, Signaling, Signalling, Agents, General, Ca2+, Ionophore, Ionophores, Tocris Bioscience, General Calcium Signaling Agent products

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